4s2™ Thermal Sealer
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Upgraded Design
- Higher pressure: deep-well plates and unevenly manufactured plates easier to seal
- Upgraded software: display instructions clearer
- More robust design: better for transportation and everyday use of the unit
Features and Benefits
- Automatic sealing process for unmatched sealing consistency
- Selectable temperature and time settings for easy optimisation of sealing conditions
- Single action operation – closing the draw initiates the process
- Rapid heating element for fast start-up
- Real time temperature display
- Auto stand-by function to save energy
- Auto switch-off function for added safety
- Works with all plate types
- Full range of heat seals available

Standard plate carrier (4ti-0615) and the optional adapter (4ti-0625) for 96well PCR plates. The two carriers can be interlocked for easy handling of shallow well plates.
Technical Data
- Weight: 9kg
- Dimensions: H310 x D275 x W181mm
- Voltage: 110/230V
- Power: 300W
- Sealing Temp. 120-200°C
The 4s2™ is a semi-automatic thermal sealer which is compatible with a wide range of seals and plates of differing designs and heights.
With variable temperature and time settings, sealing conditions are easily optimised to produce a 100% seal, eliminating sample loss.
Plate and seal are placed on the holder and once the draw is pushed closed, the sealing process is automatically controlled by an electric mechanism. This unique feature eliminates operator variation, giving a consistent seal every time and reducing the damage caused to microplates by over-sealing.
Real Time Display
The rapid heating element allows for a quick start up within minutes. The temperature is displayed in real time so that the heating up process can be monitored.
Energy Saving Functions
When the unit is left idle it automatically switches into stand-by mode during which the temperature of the heating element is reduced to 60°C to save energy. When the sealer is left idle for longer periods it switches off automatically for added safety. The times at which the unit switches into stand-by and switch-off modes can be adjusted to suit the user’s needs.
Adapters and Sealing Aids
The 4s2 employs a unique and cost saving adapter system. Deep well plates and most other skirted plates can be sealed on the standard plate carrier (4ti-0615, supplied with the unit). For all 96well PCR plates an additional plate carrier (4ti-0625, optional extra) must be used. Both plate carriers can also be combined for easier handling of shallow well plates such as 384well PCR plates.
For better sealing of those films which have a tendency to curl we offer sealing aids. A weighted platen (4ti-0602) for use with deep well blocks is provided with the unit and a sealing frame for use with all other plate designs is supplied when ordering the optional 4ti-0625 adapter.
Plate Formats
The following plate formats can be used with an appropriate holder:
- SBS standard polypropylene & polystyrene plates & deepwell blocks
- PCR plates including skirted, semi-skirted and non-skirted formats
4s2 operation in 6 easy steps!

| Code | Description | Details |
| 4ti-0650 | 4s2™ Thermal Sealer incl. universal power supply, power cord, manual, standard plate adapter (4ti-0615) and seal platen (4ti-0602) | 1 |
| 4ti-0615* | Adapter for skirted 96well and 384well plates | 1 |
| 4ti-0616 | Adapter for Roche 1536well PCR plate | 1 |
| 4ti-0602* | Weighted platen to hold down sealing sheets that have a tendency to curl | 1 |
| 4ti-0625 | Adapter for 96well PCR plates, includes sealing frame (4ti-0612) | 1 |
| 4ti-0612 | Sealing frame for use with 4ti-0625 adapter | 1 |
